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Pattern 1: Rapid regain (approximately 40% of discontinuations)

Verdict: Limited evidence BPC-157 has a credible biological rationale, but showing that something could work through a plausible mechanism is not the same as proving it does work in humans [13]

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Research suggests that both have promise on their own: a large umbrella meta?analysis recently found that berberine supplementation significantly reduced fasting blood glucose (by about 0.77?mmol/L) and HbA1c (by 0.57?%) in people with metabolic disorders